The water doesn’t make a difference. What’s killing the bacteria is the heat. The water just changes the method of heat transfer. But as others have already said, killing the bacteria may not necessarily make it safe
The water doesn’t make a difference. What’s killing the bacteria is the heat. The water just changes the method of heat transfer. But as others have already said, killing the bacteria may not necessarily make it safe
The pancreas is not really stable enough to be implanted in at all. Other organs you’re imagining like liver, stomach, heart, etc. have a solid lining that can be cut open and stitched back together. The pancreas is more like a cluster of loose cells with veins throughout and held together by a very thin, tissue paper lining. If you try to open it and insert cells, you’re not going to be able to put it back together.
That’s why cells are usually put in the liver, which has a large vein going directly to the pancreas. Close proximity and high blood supply. Implanting in the pancreas will likely never be an option unless you can drastically reduce the volume of cells.
Our lab was working on implanting the stem cells on a porous scaffold in the fat pad of the stomach as an alternative
Unfortunately, that doesn’t necessarily negate the requirement for immunosuppresors or some other kind of immuno protection. If it is Type 1 diabetes, the person originally became diabetic because the immune system saw certain markers on the beta cells (insulin producing cells) as a threat. So, if you recreate the beta cells, there is still a possibility that it will happen again. You are fighting your own immune system. Someone in our lab was studying encapsulation of cells to create a protective barrier around them for this very issue
If the person was Type 2, this might be less of a risk since type 2 can also be due to high insulin resistivity. There are a lot of other factors involved, though, it’s not straightforward
I literally worked in a research lab working on islet cell therapies for diabetes in the US. This has actually been done many times before with cells from cadavers. It has been successful, although most the of the time the person reverts back after a few years
The issues we were trying to solve in the lab were
Finding a good place to transplant where the cells will last: Implanting in the hepatic region (liver), which is the most common place to implant, is toxic to the cells over time hence only lasting 3-5 years. The cells need a really good blood supply and the volume you’re transplanting can’t be easily transplanted in the pancreas or kidney capsules (where many successful studies were performed in mice and rats)
Being able to consistently make a high volume of stem cells that are fully grown into insulin producing cells: Cadaver cells usually require 3-5 donors for 1 person and require the receiver to be on lifelong immunosuppresors due to the immune response. Depending on the kind of stem cells, the patient may still even need immunosuppresors due to the cell type you’re converting from
All this the say - the article says nothing about where the cells where transplanted, where they came from, or whether the person has Type 1 or Type 2 diabetes. Although it is still a feat, it is likely not the first time it has been done, and we’re still a long ways off from a cure
Dr. Death was about gross negligence in medicine and the failure of the medical system to prevent unqualified doctors from making it through the system. There’s no evidence that this study has anything to do with that
None of those are mammals…
This title really overly praises him for 1) not doing much at all and 2) making changes that should have been made months ago
If you actually watch the documentary they also talk about 2 pedophiles who were on his set at nick and convicted during that time and one pedophile who was convicted from a disney set.
It’s less about Dan schneider specifically (although he does seem to have a lot of unprofessional, sexist, and inappropriate mannerisms) and more about the need to increase protections for the physical and mental well being of child actors as a whole
The bad part is that their healthcare system still has to deal with the rising number of cases, but it’s not like there has been an unexpected spike from anything unusual
For those who dont feel like reading the whole article, here’s why:
“Much of the increase in kidney failure is caused by an ageing population. When age is taken into account, the number of people with kidney failure as a proportion of the population has remained fairly stable over the past decade, according to data from the registry.”
I dont agree with their views, but I really dont think it’s affecting their demand as much as you think. Lines are always insanely long - they just move them through very efficiently. By taking orders/payment as soon as you enter the line and knowing which car to give the food to when you get close to the window, the line never stops moving
I feel like Jimmy johns and chick fil a are the only truly fast restaurants anymore. For JJ you do have to go inside, but they often make your sandwich and complete payment in less than a minute, maybe 5 minutes max.
Meanwhile I’ve been to other drive throughs where even with very few people in line, it somehow takes 10/15 mins to get your meal. Plus, it’s often incorrectly made and expensive
New fear unlocked
Did you use melted or soft butter? Did you refrigerate the dough before baking?
We would need to know more about the recipe and what you did while baking to know for sure
Testosterone does increase risk of heart failure so that is certainly part of it.
Women are also more risk-averse. Risky living = high chance of dying https://m.economictimes.com/magazines/panache/men-have-a-shorter-life-expectancy-than-women-thanks-to-their-genes-says-harvard-study/articleshow/99119402.cms
It sounds like if you’re trying all of this and it’s still not working, something about the way you’re selling yourself isn’t working. Have you tried changing your resume to better match different job descriptions? Try having someone give you feedback on the way you interview. Are you coming on too strong? Maybe you dont have enough specific examples in your answers or too many specifics and not enough leadership/direction. I would also use LinkedIn if you’re not already
Really great shows have a broader plot premise and are free to build new storylines and character arcs each season. As YoBuckStopsHere said, some great shows build up and grow overtime - think Breaking Bad, Parks and Rec. Both shows start off slower, focus on character building in the earlier seasons. Then they become plot focused later on.
Other shows have the flexibility to create new story arcs so each season almost stands on its own but they still stay within the larger overarching premise, example - The Great, Game of thrones (although they really gave up at the end)
I think good shows have a plan for how to get to the end and mediocre shows do as OP described - have a beginning and end planned and not much in the middle. I don’t think all shows are stuck in Act 2, but it does say something that the ones that aren’t stuck there stand out that much more
Boiled meat tastes bad because you’re not adding oil/butter. You’re also not applying enough direct heat (plus keeping it too moist) to create the maillard reaction that is needed for a crust to form