Genes capable of creating antibiotic-resistant superbugs have been detected in the UK’s largest lake, which supplies drinking water to about 40% of Northern Ireland.

Testing of water from Lough Neagh, which has a surface area 26 times bigger than Windermere, found genes resistant to a wide range of antibiotics, including carbapenems – drugs reserved for life-threatening infections when all other treatments have failed.

The discovery comes as deaths linked to antibiotic-resistant infections are rising worldwide. Nearly 400 resistant infections are reported each week in England, with deaths linked to them reaching an estimated 2,379 in 2024, according to UK Health Security Agency data.

The World Health Organization (WHO) describes this antimicrobial resistance (AMR) as “one of the most urgent, complex and frightening health challenges of our time”.