If it’s any consolation, prion disease occurance is almost entirely genetic. The mad cow scare in the EU in the early 00’s is really the only major case of a threat within the food supply, and it was pretty quickly fixed by changing how animals are handled (especially sick ones). Outside of that, the only other transmission between hosts has been observed in tribal rituals involving eating the brain of a loved one after they die, and improperly sterilized medical instruments used during brain/spinal surgery.

So don’t eat human brain and make sure that you’re getting your brain surgery done with either new instruments or ones that have been properly autoclaved and you should be good as long as you don’t just randomly get CJD due to genetics. Not much you can do about that, though.

You’ll probably get done in by heart disease, a car accident, and lightning a couple of dozen times before you need to worry about contracting a prison diseases.